During aboriginal 1980s Chinese scientists, by serendipity, apparent that artemether was not alone an antimalarial agent, but aswell able adjoin the claret flukes. Eventually, class abstracts accept accepted the ample spectrum of action adjoin altered trematodes, including all animal schistosomes, Clonorchis sinensis, Fasciola hepatica and Opisthorchis viverrini.These studies appear that artemether exhibits the accomplished action adjoin adolescent stages of the trematodes, while developed worms are decidedly beneath susceptible. In addition, there are no break of neurotoxicity afterward again top doses. Randomized controlled analytic trials accepted that artemether, orally administered at a dosage of 6 mg/kg already every 2–3 weeks, after-effects in no drug-related adverse effects, and decidedly reduces the accident and acuteness of schistosome infections, including those of Scistosoma mansoni, S. japonicum and S. haematobium
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