Ampicillin is used to amusement infections by abounding Gram-positive and Gram-negative bacteria. Ampicillin was the aboriginal ‘broad spectrum’ penicillin with activity adjoin Gram-positive bacilli including Streptococcus pneumoniae, Streptococcus pyogenes, some isolates of Staphylococcus aureus (but not penicillin-resistant or methicillin-resistant strains), and some Enterococcus. Activity adjoin Gram-negative bacilli includes Neisseria meningitidis, some Haemophilus influenzae, and some of the Enterobacteriaceae. Its spectrum of activity is added by co-administration of sulbactam, a biologic that inhibits beta lactamase, an agitator produced by bacilli to inactivate ampicillin and accompanying antibiotics.It is sometimes used in aggregate with added antibiotics that accept altered mechanisms of action, like vancomycin, linezolid, daptomycin, and tigecycline.
Ampicillin can be administered by mouth, an intramuscular bang (shot) or by intravenous infusion.