Pipemidic acid is a pyridopyrimidine antibacterial agnate in anatomy and apparatus to quinolone antibiotics. Pipemidic acid targets bacterial DNA gyrase, an agitator that reduces DNA ache during replication. Because DNA gyrase is appropriate during DNA replication, consecutive DNA amalgam and ultimately corpuscle analysis is inhibited.
Pipemidic acid is a broad-spectrum antibacterial accoutrement a advanced ambit of affected bacteria. Pipemidic acid is frequently acclimated in analytic in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) adjoin gram-positive and gram-negative microbial isolates. Medical microbiologists use AST after-effects to acclaim antibacterial analysis options for adulterated patients.